Primary impairment of left ventricular function in Marfan syndrome

Cardiovascular involvement in Marfan syndrome is mainly characterized by progressive dilatation of the proximal aorta. Whether left ventricular dysfunction is present in these patients is not clear at present.Assess left ventricular function in patients with Marfan syndrome, free of significant valvular heart disease, using a combination of MRI and Tissue Doppler imaging (TDI).A total of 26 Marfan patients (mean age=32.0+/-10.9, 12 men) without...