Original paper

Stn1 is critical for telomere maintenance and long‐term viability of somatic human cells

Volume: 14, Issue: 3, Pages: 372 - 381
Published: Feb 14, 2015
Abstract
Disruption of telomere maintenance pathways leads to accelerated entry into cellular senescence, a stable proliferative arrest that promotes aging-associated disorders in some mammals. The budding yeast CST complex, comprising Cdc13, Stn1, and Ctc1, is critical for telomere replication, length regulation, and end protection. Although mammalian homologues of CST have been identified recently, their role and function for telomere maintenance in...
Paper Details
Title
Stn1 is critical for telomere maintenance and long‐term viability of somatic human cells
Published Date
Feb 14, 2015
Journal
Volume
14
Issue
3
Pages
372 - 381
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