Original paper

Apolipoprotein CIII overexpressing mice are predisposed to diet‐induced hepatic steatosis and hepatic insulin resistance

Volume: 54, Issue: 5, Pages: 1650 - 1660
Published: Aug 19, 2011
Abstract
Nonalcoholic fatty liver disease (NAFLD) and insulin resistance have recently been found to be associated with increased plasma concentrations of apolipoprotein CIII (APOC3) in humans carrying single nucleotide polymorphisms within the insulin response element of the APOC3 gene. To examine whether increased expression of APOC3 would predispose mice to NAFLD and hepatic insulin resistance, human APOC3 overexpressing (ApoC3Tg) mice were...
Paper Details
Title
Apolipoprotein CIII overexpressing mice are predisposed to diet‐induced hepatic steatosis and hepatic insulin resistance
Published Date
Aug 19, 2011
Journal
Volume
54
Issue
5
Pages
1650 - 1660
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