Structure of anti-peptide antibody complexes
Abstract
Several binding scaffolds that are not based on immunoglobulins have been designed as alternatives to traditional monoclonal antibodies. Many of them have been developed to bind to folded proteins, yet cellular networks for signaling and protein trafficking often depend on binding to unfolded regions of proteins. This type of binding can thus be well described as a peptide–protein interaction. In this review, we compare different peptide-binding...
Paper Details
Title
Structure of anti-peptide antibody complexes
Published Date
Jan 1, 1994
Journal
Volume
145
Issue
1
Pages
73 - 85
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