Hmi1p from Saccharomyces cerevisiae Mitochondria Is a Structure-specific DNA Helicase
Volume: 280, Issue: 26, Pages: 24322 - 24329
Published: Jul 1, 2005
Abstract
Hmi1p is a Saccharomyces cerevisiae mitochondrial DNA helicase that is essential for the maintenance of functional mitochondrial DNA. Hmi1p belongs to the superfamily 1 of helicases and is a close homologue of bacterial PcrA and Rep helicases. We have overexpressed and purified recombinant Hmi1p from Escherichia coli and describe here the biochemical characteristics of its DNA helicase activities. Among nucleotide cofactors, the DNA unwinding by...
Paper Details
Title
Hmi1p from Saccharomyces cerevisiae Mitochondria Is a Structure-specific DNA Helicase
Published Date
Jul 1, 2005
Volume
280
Issue
26
Pages
24322 - 24329
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