CRISPR-Cas systems for editing, regulating and targeting genomes
Abstract
Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by many biological researchers. This widespread adoption has been largely fueled by the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) technology, an important new approach for generating RNA-guided nucleases, such as Cas9, with customizable specificities. Genome editing mediated by...
Paper Details
Title
CRISPR-Cas systems for editing, regulating and targeting genomes
Published Date
Mar 2, 2014
Journal
Volume
32
Issue
4
Pages
347 - 355
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Notes
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