Some Naturrally Occurring Skin Irritants

: Thirteen esters were isolated from the fresh latex of four species of the genus Euphorbia . Structures were elucidated by infra‐red, nuclear magnetic resonance and mass‐spectroscopy, together with circular dichroism spectroscopy, of the esters and their derivatives or hydrolysis products. Eight of these compounds were new esters of 12‐deoxy‐phorbol. All the isolated esters produced inflammation of the skin and their relative potencies were...