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Richard J. Schmidt
Cardiff University
DermatologyChemistryBiochemistryMedicineBiology
59Publications
20H-index
1,249Citations
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Publications 55
Newest
#1Paola Lucia Minciullo (UNIME: University of Messina)H-Index: 18
#2Gioacchino Calapai (UNIME: University of Messina)H-Index: 36
Last. Richard J. SchmidtH-Index: 20
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Summary This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph – now (since 2014) called a ‘European Union herbal monograph’ – has been produced. The present part 4 addresses species from Solidago virgaurea L. to Vitis vinifera L.
1 CitationsSource
#1Gioacchino Calapai (UNIME: University of Messina)H-Index: 36
#2Paola Lucia Minciullo (UNIME: University of Messina)H-Index: 18
Last. Richard J. SchmidtH-Index: 20
view all 6 authors...
Summary This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph – now (since 2015)† called a European Union herbal monograph – has been produced. Part 3: Mentha × piperita L.–Solanum dulcamara L.
4 CitationsSource
#1Sebastiano Gangemi (UNIME: University of Messina)H-Index: 30
#2Paola Lucia Minciullo (UNIME: University of Messina)H-Index: 18
Last. Richard J. SchmidtH-Index: 20
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This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph has been produced. Part 2: Echinacea purpurea Moench–Lavandula angustifolia Mill.
9 CitationsSource
#1Gioacchino Calapai (UNIME: University of Messina)H-Index: 36
#2Marco Miroddi (UNIME: University of Messina)H-Index: 9
Last. Richard J. SchmidtH-Index: 20
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Summary This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph has been produced. Part 1: Achillea millefolium L.–Curcuma longa L.
18 CitationsSource
#1Georges DucombsH-Index: 1
#2Richard J. SchmidtH-Index: 20
Contact dermatitis from plants or plant products may occur by several mechanisms. The most common dermatoses seen in dermatology clinics are delayed and immediate contact reactions of allergic aetiology. Not so commonly seen are reactions of irritant aetiology, which may be mechanically or chemically induced. Photoallergic reactions seem to be very rare but photoirritant reactions do occur quite commonly. Reactions of mixed aetiology, for instance irritant reactions superimposed on allergic reac...
27 CitationsSource
#1Fred J. Evans (Lond: University of London)H-Index: 25
#2A. D. Kinghorn (Lond: University of London)H-Index: 2
Last. Richard J. Schmidt (Lond: University of London)H-Index: 20
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: Thirteen esters were isolated from the fresh latex of four species of the genus Euphorbia. Structures were elucidated by infra-red, nuclear magnetic resonance and mass-spectroscopy, together with circular dichroism spectroscopy, of the esters and their derivatives or hydrolysis products. Eight of these compounds were new esters of 12-deoxy-phorbol. All the isolated esters produced inflammation of the skin and their relative potencies were assessed by the mice ear test for irritant effects. The...
17 CitationsSource
#1Fred J. Evans (Lond: University of London)H-Index: 25
#2Richard J. Schmidt (Lond: University of London)H-Index: 20
The latex of Euphorbia poissonii was found to contain irritant aromatic diterpene esters based upon resiniferonol, 12-deoxy-16-hydroxy-phorbol and 12-deoxyphorbol. Four resiniferonol esters, 9,13,14-ortho-phenylacetyl-resiniferonol-20-0-[p-hydroxy-phenylacetate]; 9,13,14-orthophenylacetyl-resiniferonol-20-0-[m-methoxy-m′-hydroxy-phenylacetate]; 9,13,14-orthophenylacetyl-resiniferonol-20-0-acetate and resiniferonol-14-0-phenylacetate-20-0-[m-methoxy-m′-hydroxy-phenylacetate], were identified. Two...
15 CitationsSource
3 CitationsSource
#1Breda Cullen (Johnson & Johnson)H-Index: 9
#2Paul William Watt (Johnson & Johnson)H-Index: 2
Last. Nicholas D. Light (Johnson & Johnson)H-Index: 2
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Abstract Normal wound healing is a carefully controlled balance of destructive processes necessary to remove damaged tissue and repair processes which lead to new tissue formation. Proteases and growth factors play a pivotal role in regulating this balance, and if disrupted in favour of degradation then delayed healing ensues; a trait of chronic wounds. Whilst there are many types of chronic wounds, biochemically they are thought to be similar in that they are characterised by a prolonged inflam...
132 CitationsSource
Abstract An account is provided of the history and planned development of BoDD: Botanical Dermatology Database, a major Internet resource.
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