The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

Richard Guerrant and colleagues discuss the growing evidence that vicious cycles of early childhood enteric infections and malnutrition are associated with obesity and its comorbidities in later life, forming a triple burden of poverty. The potential mechanisms and interventions that must be understood and applied to prevent this loss of human potential are also presented. More than one-fifth of the world's population live in extreme poverty,...