New developments in the role of α1-adrenergic receptors in cardiovascular disease

Summary null null In recent years, success in the management of hypertension has not been convincingly translated into a significant reduction in mortality rates due to coronary heart disease. One possible explanation is that adverse changes in plasma lipid levels that are produced by some of the antihypertensive drugs may increase the metabolic risk of coronary heart disease and offset the benefits of lowering blood pressure. Recently, α 1...