Bioefficacy of Tea Catechins Associated with Milk Caseins Tested Using Different In Vitro Digestion Models

Milk proteins, and in particular caseins, are avid binders of polyphenols. The objective of this work was to understand how the presence of a polyphenol–casein complex may affect the bioefficacy of tea catechins [epigallocatechin-3-gallate (EGCG)]. In vitro digestion was carried out using two different models: a batch model and a dynamic digestion model, using a simulator of the human intestinal microbial ecosystem (SHIME). SDS-PAGE...