Original paper

Key issues in non-viral gene delivery

Volume: 34, Issue: 1, Pages: 3 - 19
Published: Oct 1, 1998
Abstract
The future of non-viral gene therapy depends on a detailed understanding of the barriers to delivery of polynucleotides. These include physicomechanical barriers, which limit the design of delivery devices, physicochemical barriers that influence self-assembly of colloidal particulate formulations, and biological barriers that compromise delivery of the DNA to its target site. It is important that realistic delivery strategies are adopted for...
Paper Details
Title
Key issues in non-viral gene delivery
Published Date
Oct 1, 1998
Volume
34
Issue
1
Pages
3 - 19
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