Complement modulation in solid-organ transplantation
Abstract
The complement system is a major constituent of the innate immune system. It has a critical role in defense against pathogens but dysregulation of complement activation may lead to tissue injury and modulate the adaptive immune response. In organ transplantation, local complement activation is involved in hyper-acute rejection and antibody-mediated rejection. This last decade, interest in complement activation has increased due to new insights...
Paper Details
Title
Complement modulation in solid-organ transplantation
Published Date
Jul 1, 2014
Journal
Volume
28
Issue
3
Pages
119 - 125
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Notes
History