Triethyltin Interferes with Ca2+Signaling and Potentiates Norepinephrine Release in PC12 Cells
Volume: 140, Issue: 2, Pages: 289 - 295
Published: Oct 1, 1996
Abstract
We have investigated the effects of triethyltin (TET) on agonist-stimulated Ca2+signaling and neurosecretion in PC12 cells. Treatment of PC12 cells with 10 μMTET elicited a slow increase of the resting cytosolic free Ca2+concentration due to Ca2+release from intracellular stores. Furthermore, TET modified the Ca2+responses elicited by bradykinin (Bk), adenosine triphosphate (ATP), or high K+. TET potentiated the peak Ca2+response stimulated by...
Paper Details
Title
Triethyltin Interferes with Ca2+Signaling and Potentiates Norepinephrine Release in PC12 Cells
Published Date
Oct 1, 1996
Volume
140
Issue
2
Pages
289 - 295
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