Once‐daily initiation of basal insulin as add‐on to metformin: a 26‐week, randomized, treat‐to‐target trial comparing insulin detemir with insulin glargine in patients with type 2 diabetes

Aims This study assessed the efficacy and safety of once‐daily insulin initiation using insulin detemir (detemir) or insulin glargine (glargine) added to existing metformin in type 2 diabetes ( T2D ). Methods This 26‐week, multinational, randomized, treat‐to‐target trial involved 457 insulin‐naïve adults with T2D ( HbA1c 7–9%). Detemir or glargine was added to current metformin therapy [any second oral antidiabetic drug ( OAD ) discontinued] and...