Review paper

Processing strategies and software solutions for data‐independent acquisition in mass spectrometry

Volume: 15, Issue: 5-6, Pages: 964 - 980
Published: Feb 2, 2015
Abstract
Data‐independent acquisition (DIA) offers several advantages over data‐dependent acquisition (DDA) schemes for characterizing complex protein digests analyzed by LC‐MS/MS. In contrast to the sequential detection, selection, and analysis of individual ions during DDA, DIA systematically parallelizes the fragmentation of all detectable ions within a wide m/z range regardless of intensity, thereby providing broader dynamic range of detected...
Paper Details
Title
Processing strategies and software solutions for data‐independent acquisition in mass spectrometry
Published Date
Feb 2, 2015
Journal
Volume
15
Issue
5-6
Pages
964 - 980
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