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#1Andreas HentschelH-Index: 2
#2Robert Ahrends (University of Vienna)H-Index: 1
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#1Venkateswaran Natarajan (NUS: National University of Singapore)
#2Ritu Chawla (NUS: National University of Singapore)H-Index: 1
Last. Karthik Mallilankaraman (NUS: National University of Singapore)H-Index: 19
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Aging is a natural biological process in living organisms characterized by receding bioenergetics. Mitochondria are crucial for cellular bioenergetics and thus an important contributor to age-related energetics deterioration. In addition, mitochondria play a major role in calcium signaling, redox homeostasis, and thermogenesis making this organelle a major cellular component that dictates the fate of a cell. To maintain its quantity and quality, mitochondria undergo multiple processes such as fi...
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#1Yue Zhu (SJTU: Shanghai Jiao Tong University)
#2Yaohui Huang (SJTU: Shanghai Jiao Tong University)
Last. Qiang Tian (SJTU: Shanghai Jiao Tong University)
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Hematological diseases, including leukemia, lymphoma and multiple myeoloma, are characterized by high heterogeneity with diverse cellular subpopulations. Single-cell RNA sequencing (scRNA-seq), a transformational technology, provides deep insights into cell-to-cell variation in tumor and microenvironment, allows high resolution dissection of the pathogenic mechanisms of diseases, and affords potential clinical utilities. We summarize recent development in single cell transcriptomics and associat...
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#1Hui Liu (University of Newcastle)
#2Xiang Li (University of Newcastle)H-Index: 1
Last. Hubert Hondermarck (University of Newcastle)H-Index: 36
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Pancreatic cancer has a dismal prognosis and to date there are no targeted therapies for this malignancy. Using shotgun proteomics, the mRNA binding protein Cold Shock Domain Containing E1 (CSDE1), also called Upstream-of-N Ras (UNR), was detected in pancreatic cancer cell lines but not in normal pancreatic epithelial cells. The expression of CSDE1 in pancreatic cancer cells was confirmed by Western-blotting and immunohistochemistry of human pancreatic tumors. In vitro functional assays showed t...
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Last. Brian K. Kennedy (Agency for Science, Technology and Research)H-Index: 5
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#1Nataly Kravchenko-Balasha (HUJI: Hebrew University of Jerusalem)H-Index: 10
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#1Arunima SinhaH-Index: 2
Last. Subhra ChakrabortyH-Index: 21
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Nutrient dynamics in storage organs is a complex developmental process that requires coordinated interactions of environmental, biochemical, and genetic factors. Although sink organ developmental events have been identified, our understanding of translational and post-translational regulation of reserve synthesis, accumulation and utilization in legume crops is limited. To understand nutrient dynamics during embryonic and cotyledonary photoheterotrophic transition to mature and germinating autot...
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#1Michael Kohl (RUB: Ruhr University Bochum)H-Index: 12
#2Markus Stepath (RUB: Ruhr University Bochum)
Last. Martin Eisenacher (RUB: Ruhr University Bochum)H-Index: 31
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#1Leon L. Xu (U of T: University of Toronto)
#2Adamo Young (U of T: University of Toronto)
Last. Hannes L. Röst (U of T: University of Toronto)H-Index: 24
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#1Monika Dvorakova (Masaryk University)H-Index: 3
#2Petr Lapcik (Masaryk University)
Last. Pavel Bouchal (Masaryk University)H-Index: 12
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