Dynamics of protein precrystallization cluster formation

In the initial stages of crystallization of hen egg-white lysozyme, monomers aggregate rapidly and form large precrystallization fractal clusters, as shown by photon correlation spectroscopy (PCS). The growth of these clusters resembles closely that of inorganic colloids taking place either in the reaction limited (RLCA), crossover (XOVER), or diffusion limited (DLCA) cluster aggregation regimes [see Lin et al., Colloid Interface Sci. 137 (1990)...