Original paper

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

Cell45.50
Volume: 160, Issue: 1-2, Pages: 74 - 87
Published: Jan 1, 2015
Abstract
Type 2 innate lymphoid cells (ILC2s), an innate source of the type 2 cytokines interleukin (IL)-5 and -13, participate in the maintenance of tissue homeostasis. Although type 2 immunity is critically important for mediating metabolic adaptations to environmental cold, the functions of ILC2s in beige or brown fat development are poorly defined. We report here that activation of ILC2s by IL-33 is sufficient to promote the growth of functional...
Paper Details
Title
Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis
Published Date
Jan 1, 2015
Journal
Volume
160
Issue
1-2
Pages
74 - 87
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