Study on the amount of binding of anti-tumor metal complexes to different target sites of dGMP using trans-[en2Os(η2-H2)(CF3SO3)](CF3SO3) in a competitive mode

In order to investigate the binding sites and the amount of binding of a number of anti-tumor metal complexes (cisplatin, Cp2TiCl2 and (CH3)2SnCl2) to target molecule DNA mononucleotides in aqueous solution, a 1H NMR recognition probe, trans-[en2Os(η2-H2)(CF3SO3)](CF3SO3), was used in a competitive mode. The minimum percentages of binding of anti-tumor metal complexes to different sites of dGMP were also...