Journal of Inorganic Biochemistry
IF
3.06
Papers
9847
Papers 9824
1 page of 983 pages (9,824 results)
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Published on Mar 1, 2019in Journal of Inorganic Biochemistry 3.06
Hongen Guo3
Estimated H-index: 3
(Taiyuan University of Technology),
Yixia Zhang2
Estimated H-index: 2
(Taiyuan University of Technology)
+ 5 AuthorsWai-Yeung Wong69
Estimated H-index: 69
(Taiyuan University of Technology)
Abstract In this work, we present the development of a high water soluble biological nanoprobe through the covalent bonding of β-CD onto the surface of iron oxide‑gold nanoclusters (Fe 3 O 4 @Au@β-CD). Fe 3 O 4 @Au@SiO 2 NPs were also prepared for comparison. The maximum emission peak of magnetic fluorescent NPs red-shifted by 30 nm and the lifetime was also elongated to 5.21 μs after surface modified with β-CD. The relaxivities and in vitro magnetic resonance imaging ability of the resultant ma...
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Published on Apr 1, 2019in Journal of Inorganic Biochemistry 3.06
Gabriel H. Ribeiro (Federal University of São Carlos), Legna Colina-Vegas7
Estimated H-index: 7
(Federal University of São Carlos)
+ 3 AuthorsAlzir A. Batista26
Estimated H-index: 26
(Federal University of São Carlos)
Abstract The rational design of anticancer agents that acts in specific biological targets is one of the most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new ruthenium (II) compounds with good cytotoxicity against tumor cells, a series of new complexes of general formula [RuCl(PPh 3 )(Hdpa)(N N)]Cl [PPh 3 = triphenylphosphine, N-N = 2,2′-dipyridylamine (Hdpa) ( 1 ), 1,2-diaminoethane (en) ( 2 ), 2,2′-bipyridine (bipy) ( 3 ), 5,5′-dimethyl-2,2′-bipyridine (dmb...
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Published on Jan 1, 2019in Journal of Inorganic Biochemistry 3.06
Dai Cheng1
Estimated H-index: 1
(Tianjin University),
Xinyu Zhang1
Estimated H-index: 1
(Tianjin University)
+ 3 AuthorsShuo Wang1
Estimated H-index: 1
(Nankai University)
Abstract Aluminum (Al), which may bring about damage to the macrophages, has been implicated in the development of immunological diseases. It has been reported that chlorogenic acid (CGA, 5‑caffeoylquinic acid, chemical formula: C 16 H 18 O 9 ) is a natural antioxidant and chelating agent with the capacity against Al (III)-induced biotoxicity. The present study was carried out to investigate whether CGA could reduce AlCl 3 -induced cellular damage in RAW264.7 cells. After treatment with AlCl 3 ,...
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Published on Mar 1, 2019in Journal of Inorganic Biochemistry 3.06
Zhong-Gui Gong (Shandong Agricultural University), Xin-Yu Wang3
Estimated H-index: 3
(Shandong Agricultural University)
+ 2 AuthorsLin Wang10
Estimated H-index: 10
(Shandong Agricultural University)
Abstract Cadmium (Cd) is a ubiquitously distributed environmental pollutant that is highly toxic to liver. Trehalose (Tr), a novel autophagy activator, has been shown to exert cytoprotective effect in numerous pathological processes. However, it is yet to be established whether Tr affords protection against Cd-induced hepatotoxicity. Here, we aimed to investigate the protective effect of Tr on Cd-induced hepatic injury in rats. First, Cd-elevated serum hepatic enzymes and liver pathological chan...
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Published on Feb 1, 2019in Journal of Inorganic Biochemistry 3.06
R. Musacco Sebio (University of Buenos Aires), Nidia Ferrarotti5
Estimated H-index: 5
(University of Buenos Aires)
+ 5 AuthorsMarisa G. Repetto13
Estimated H-index: 13
(University of Buenos Aires)
Abstract Male rats of 80–90 g were overloaded with either Fe(II) or Cu(II) for 42 days by high concentrations of FeCl 2 or CuSO 4 in the drinking water. The animals were fed with a commercial rodent diet of 2780 kcal/100 g. Both metal treatments led to a liver redox imbalance and dyshomeostasis with oxidative stress and damage and the concomitant enhancement of oxidative processes as indicated by in vivo surface liver chemiluminescence, the sensitive and organ non-invasive assay for oxidative fr...
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Published on May 1, 2019in Journal of Inorganic Biochemistry 3.06
Shun Hirota30
Estimated H-index: 30
(Nara Institute of Science and Technology)
Abstract Oligomerization of heme proteins is useful for construction of new materials with cooperative and systematic functions; thus, diverse methods have been applied for construction of artificial heme protein oligomers. Three-dimensional (3D) domain swapping is a protein oligomerization phenomenon that exchanges the same domain or secondary structural element between molecules. 3D domain swapping was first reported in 1994; since then many proteins have been reported to domain swap. Our rese...
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Published on Mar 1, 2019in Journal of Inorganic Biochemistry 3.06
Qiong Zhang41
Estimated H-index: 41
(Anhui University),
Mingzhu Zhang5
Estimated H-index: 5
(Anhui University)
+ 7 AuthorsYupeng Tian34
Estimated H-index: 34
(Anhui University)
Abstract Compared to organotin (IV) compounds with biochemical activity, two-photon absorption (2PA) organotin (IV) complexes for targeting nuclear with anticancer activities are rarely reported. Here, two novel 2PA organotin (IV) cyano carboxylate complexes ( C1Sn - 1 , C1Sn - 2 ) are synthesized and characterized. The two-photon absorption cross section values (δ) in the near-infrared region are significantly enhanced for C1Sn - 2 compared to C1Sn - 1 , thus developing for targeting nuclear by...
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Published on Apr 1, 2019in Journal of Inorganic Biochemistry 3.06
Máté Kozsup1
Estimated H-index: 1
(University of Debrecen),
Etelka Farkas27
Estimated H-index: 27
(University of Debrecen)
+ 4 AuthorsPéter Buglyó23
Estimated H-index: 23
(University of Debrecen)
Abstract Nine novel cobalt(III) ternary complexes bearing 4N donor ligands (tris(2-aminoethyl)amine (tren) or tris(2-methylpyridyl)amine (tpa)) and (fluoro)quinolones (quinH) with antibacterial and potential antitumor activity have been synthesized, characterized and screened in various biological assays. The molecular structures of [Co(tpa)(nal)](PF 6 ) 2 ( 3 ) and [Co(tpa)(nor)(Co(tpa)(norH)](PF 6 ) 3 (Cl) 2 ∙5MeOH ( 8 ) (nal = deprotonated form of nalidixic acid, norH = norfloxacin) with the ...
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Published on Apr 1, 2019in Journal of Inorganic Biochemistry 3.06
Clara Gerosa15
Estimated H-index: 15
(University of Cagliari),
Daniela Fanni16
Estimated H-index: 16
(University of Cagliari)
+ 4 AuthorsGavino Faa28
Estimated H-index: 28
(University of Cagliari)
Abstract Wilson’s disease (WD) is a genetic metabolic disease strictly associated with liver cirrhosis. In this review, the genetic bases of the disease are discussed, with emphasis on the role of ATP7B (the Wilson disease protein) dysfunction as a determinant factor of systemic copper overload. Regarding the different multiple mutations described in WD patients, the peculiarity of Sardinian population is highlighted, Sardinians carrying a rare deletion in the promoter (5′ UTR) of the WD gene. T...
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