Daily rhythms of glycerophospholipid synthesis in fibroblast cultures involve differential enzyme contributions
Abstract
Circadian clocks regulate the temporal organization of several biochemical processes, including lipid metabolism, and their disruption leads to severe metabolic disorders. Immortalized cell lines acting as circadian clocks display daily variations in [(32)P]phospholipid labeling; however, the regulation of glycerophospholipid (GPL) synthesis by internal clocks remains unknown. Here we found that arrested NIH 3T3 cells synchronized with a 2...
Paper Details
Title
Daily rhythms of glycerophospholipid synthesis in fibroblast cultures involve differential enzyme contributions
Published Date
Jul 1, 2013
Journal
Volume
54
Issue
7
Pages
1798 - 1811
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