Original paper

Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal

Volume: 107, Issue: 34, Pages: 15246 - 15251
Published: Aug 9, 2010
Abstract
Changes in neuronal activity are accompanied by the release of vasoactive mediators that cause microscopic dilation and constriction of the cerebral microvasculature and are manifested in macroscopic blood oxygenation level-dependent (BOLD) functional MRI (fMRI) signals. We used two-photon microscopy to measure the diameters of single arterioles and capillaries at different depths within the rat primary somatosensory cortex. These measurements...
Paper Details
Title
Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal
Published Date
Aug 9, 2010
Volume
107
Issue
34
Pages
15246 - 15251
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