Change in Inflammatory Markers and Cognitive Status in the Oldest-Old Women from the Study of Osteoporotic Fractures

To determine the association between interleukin-6 (IL-6), IL-6 soluble receptor (sR), and soluble tumor necrosis factor receptor-1 (sTNF-R1) and cognitive status in the oldest-old women.Twenty-year longitudinal cohort study.Four clinical sites in the United States.Women from the Study of Osteoporotic Fractures (N = 905; mean age 88.3 ± 2.8 at cognitive status adjudication).At Year 20, cognitive status was adjudicated as normal, mild cognitive...