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Inorganic and protein crystal growth - similarities and differences

Published on Aug 1, 1986in Journal of Crystal Growth1.573
· DOI :10.1016/0022-0248(86)90179-X
F. Rosenberger19
Estimated H-index: 19
(UofU: University of Utah)
Abstract
Abstract Transport and interface kinetics concepts that have proven successful in the design and control of inorganic crystal growth experiments are outlined. Their potential usefulness and limitations in protein crystal growth are discussed. The presentation follows a selection of observations and statements that are often made by workers in the protein crystal growth field. The paper is meant to be tutorial in nature. Emphasis is placed on concepts which bear practical significance. Though the discussion is on an introductory level, additional references are given to facilitate deeper penetration of the various topics. Suggestions for the possible improvement of current protein crystal growth techniques are made.
  • References (29)
  • Citations (94)
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References29
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#2G. Feher (UCSD: University of California, San Diego)H-Index: 3
Abstract The protein concentration dependence of the growth rate of lysozyme crystals (tetragonal form) was investigated at two NaCl concentrations (3.5%, 5% w/v). The rates for different crystallographic faces were found to have different concentration dependences, resulting in a changing crystal shape with concentration. The experimental results were compared with standard crystal growth theories. The strong concentration dependence could be fitted at high supersaturation by a two-dimensional ...
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#1Walter Littke (University of Freiburg)H-Index: 5
#2Christina John (University of Freiburg)H-Index: 3
Abstract Crystal growth conditions for proteins under microgravity were investigated with two model compounds (β-galactosidase and lysozyme). The single crystals obtained have been found to be significantly larger than those prepared in the same environment on earth.
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#1Walter Littke (University of Freiburg)H-Index: 5
#2Christina John (University of Freiburg)H-Index: 3
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#1F. Rosenberger (UofU: University of Utah)H-Index: 19
#2Georg Müller (FAU: University of Erlangen-Nuremberg)H-Index: 33
Abstract Most solid-state devices utilize properties of crystals obtained through the controlled introduction into the host lattice of impurities (“dopants”) or deviations from stoichiometry. This compositional adjustment is typically made during the growth of the solid from its nutrient (melt, vapor or solution). Since the yield and performance of devices depends strongly on their compositional uniformity, a detailed understanding of the fluid dynamics of nutrient phases and at solid-nutrient i...
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#1Alexander McPhersonH-Index: 51
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