Baseline characteristics associated with different BMI trajectories in weight loss trials: a case for better targeting of interventions

Dietary weight loss interventions have heterogeneous outcomes in long-term studies, with many participants regaining part or all of the lost weight. Growth mixture modelling is a novel analytic approach that can be used to identify different trajectories of weight change during a trial rather than focussing on the total amount of weight lost.Data were pooled from two 12-month dietary weight loss studies where no significant difference was...