Original paper
Global changes in DNA methylation in Alzheimer’s disease peripheral blood mononuclear cells
Abstract
Changes in epigenetic marks may help explain the late onset of Alzheimer's disease (AD). In this study we measured genome-wide DNA methylation by luminometric methylation assay, a quantitative measurement of genome-wide DNA methylation, on DNA isolated from peripheral blood mononuclear cells of 37 subjects with late-onset AD (LOAD) and 44 healthy controls (CT). We found an increase in global DNA methylation in LOAD subjects compared to CT...
Paper Details
Title
Global changes in DNA methylation in Alzheimer’s disease peripheral blood mononuclear cells
Published Date
Mar 1, 2015
Journal
Volume
45
Pages
139 - 144
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Notes
History