Brain Behavior and Immunity
Papers 6291
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#1Claudio LiguoriH-Index: 13
Last. Ottavia BalbiH-Index: 1
view all 15 authors...
OBJECTIVE: Coronavirus disease 2019 (COVID-19) represents a novel pneumonia leading to severe acute respiratory syndrome (SARS). Recent studies documented that SARS-Coronavirus2 (SARS-CoV2), responsible for COVID-19, can affect the nervous system. The aim of the present observational study was to prospectively assess subjective neurological symptoms (sNS) in patients with SARS-CoV2 infection. METHODS: We included patients hospitalized at the University Hospital of Rome Tor Vergata, medical cente...
Since the end of 2019, Corona Virus Disease 2019 (COVID-19) has been the cause of a worldwide pandemic. The mental status of patients with COVID-19 who have been quarantined and the interactions between their psychological distress and physiological levels of inflammation have yet to be analyzed. Using a mixed-method triangulation design (QUAN + QUAL), this study investigated and compared the mental status and inflammatory markers of 103 patients who, while hospitalized with mild symptoms, teste...
#1Ching-Fang Sun (PRC: China Medical University (PRC))
#2Wei-Che Chiu (FJU: Fu Jen Catholic University)
Last. Kuan-Pin Su (PRC: China Medical University (PRC))H-Index: 28
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Abstract Background IFN-α-induced depression in patients undergoing hepatitis C virus (HCV) treatment provides powerful support for the inflammation hypothesis of depression. Most studies have focused on the occurrence of depressive symptoms, but there has been no study yet in depression-free HCV patients receiving IFN-α. We hypothesized that HCV patients who did not develop depression after IFN-α exposure might have a lower incidence of depressive disorders after the IFN-α treatment. Methods We...
#1William Binning (UWO: University of Western Ontario)
#2Aja E. Hogan-Cann (UWO: University of Western Ontario)
Last. Wataru Inoue (UWO: University of Western Ontario)H-Index: 16
view all 11 authors...
Abstract Microglia express muscarinic G protein-coupled receptors (GPCRs) that sense cholinergic activity and are activated by acetylcholine to potentially regulate microglial functions. Knowledge about how distinct types of muscarinic GPCR signaling regulate microglia function in vivo is still poor, partly due to the fact that some of these receptors are also present in astrocytes and neurons. We generated mice expressing the hM3Dq Designer Receptor Exclusively Activated by Designer Drugs (DREA...
#1Aaron J. Grossberg (OHSU: Oregon Health & Science University)H-Index: 9
#2Elisabeth G. Vichaya (Baylor University)
Last. Robert Dantzer (University of Texas MD Anderson Cancer Center)H-Index: 93
view all 9 authors...
Abstract Fatigue is a common and debilitating symptom of cancer with few effective interventions. Cancer-related fatigue (CRF) is often associated with increases in inflammatory cytokines, however inflammation may not be requisite for this symptom, suggesting other biological mediators also play a role. Because tumors are highly metabolically active and can amplify their energetic toll via effects on distant organs, we sought to determine whether CRF could be explained by metabolic competition e...
#1Clara González-Sanguino (Complutense University of Madrid)
#2Berta Ausín (Complutense University of Madrid)H-Index: 5
Last. Manuel Muñoz (Complutense University of Madrid)H-Index: 15
view all 7 authors...
Abstract The pandemic caused by Covid-19 has been an unprecedented social and health emergency worldwide. This is the first study in the scientific literature reporting the psychological impact of the Covid-19 outbreak in a sample of the Spanish population. A cross-sectional study was conducted through an online survey of 3480 people. The presence of depression, anxiety and post-traumatic stress disorder (PTSD) was evaluated with screening tests from 14 March. Sociodemographic and Covid-19-relat...
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