The cumulative effect of genetic markers on classification performance: Insights from simple models

The cumulative effect of markers on classification accuracy, with even slight between-population allele frequency differences, has been a mainstay of empirical genetic research. The simple theoretical model of Edwards (2003) has enabled a clear elucidation of the effect of additional markers on average classification error. The present paper describes a mathematical generalization necessary to alleviate an oversimplification, but at the same...