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Tumor delivery of macromolecular drugs based on the EPR effect
Abstract
Enhanced permeability and retention (EPR) effect is the physiology-based principal mechanism of tumor accumulation of large molecules and small particles. This specific issue of Advanced Drug Delivery Reviews is summing up multiple data on the EPR effect-based drug design and clinical outcome. In this commentary, the role of the EPR effect in the intratumoral delivery of protein and peptide drugs, macromolecular drugs and drug-loaded...
Paper Details
Title
Tumor delivery of macromolecular drugs based on the EPR effect
Published Date
Mar 1, 2011
Volume
63
Issue
3
Pages
131 - 135
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