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doi.org/10.1016/j.phrs.2010.03.002

PPARγ agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells

..., Jun Fuchimoto
10
Pharmacological Research9.30
Volume: 61, Issue: 6, Pages: 489 - 498
Published: Jun 1, 2010
Abstract
Peroxisome proliferator activated (PPAR)gamma plays a critical role in the control of not only adipocyte differentiation, lipid metabolism and immunity but also the barrier functions of epithelial and endothelial cells. In the present study, to investigate effects of PPAR gamma agonists on the tight junctional barrier of human nasal epithelial cells (HNECs), hTERT-transfected HNECs, which highly express both PPAR gamma and tight junction...
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Paper Details
Title
PPARγ agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells
DOI
doi.org/10.1016/j.phrs.2010.03.002
Published Date
Jun 1, 2010
Journal
Pharmacological Research
Volume
61
Issue
6
Pages
489 - 498
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