Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
Abstract
An approach for genome analysis based on sequencing and assembly of unselected pieces of DNA from the whole chromosome has been applied to obtain the complete nucleotide sequence (1,830,137 base pairs) of the genome from the bacterium Haemophilus influenzae Rd. This approach eliminates the need for initial mapping efforts and is therefore applicable to the vast array of microbial species for which genome maps are unavailable. The H. influenzae...
Paper Details
Title
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
Published Date
Jul 28, 1995
Journal
Volume
269
Issue
5223
Pages
496 - 512
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