EFFECT OF DIET AND SMOKING INTERVENTION ON THE INCIDENCE OF CORONARY HEART DISEASE

16 202 men, aged 40-49 years, were screened for coronary risk factors, Of these, 1232 healthy, normotensive men at high risk of coronary heart disease (CHD) were selected for a 5-year randomised trial to show whether lowering of serum lipids and cessation of smoking could reduce the incidence of CHD. Men were admitted to the trial if they had serum cholesterol levels of 7.5-9.8 mmol/l (290-380) mg/dl), coronary risk scores (based on cholesterol...