Review paper
Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action
Abstract
Incretin peptides, principally GLP-1 and GIP, regulate islet hormone secretion, glucose concentrations, lipid metabolism, gut motility, appetite and body weight, and immune function, providing a scientific basis for utilizing incretin-based therapies in the treatment of type 2 diabetes. Activation of GLP-1 and GIP receptors also leads to nonglycemic effects in multiple tissues, through direct actions on tissues expressing incretin receptors and...
Paper Details
Title
Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action
Published Date
Jun 1, 2013
Journal
Volume
17
Issue
6
Pages
819 - 837
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