Adipose Depots Possess Unique Developmental Gene Signatures

We have previously demonstrated that subcutaneous and intra‐abdominal adipose tissue show different patterns of expression for developmental genes ( Shox2, En1, Tbx15 Hoxa5, Hoxc8 , and Hoxc9 ), and that the expression level of Tbx15 and Hoxa5 in humans correlated with the level of obesity and fat distribution. To further explore the role of these developmental genes in adipose tissue, we have characterized their expression in different adipose...