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Exercise tolerance in obese vs. lean adolescents: a systematic review and meta‐analysis

Published on Nov 1, 2014in Obesity Reviews8.192
· DOI :10.1111/obr.12202
Dominique Hansen23
Estimated H-index: 23
(University of Hasselt),
Nastasia Marinus2
Estimated H-index: 2
(University of Hasselt)
+ 5 AuthorsTim Takken44
Estimated H-index: 44
(UU: Utrecht University)
Abstract
Summary To prescribe feasible and medically safe exercise interventions for obese adolescents, it remains to be determined whether exercise tolerance is altered and whether anomalous cardiopulmonary responses during maximal exercise testing are present. Studies that examined cardiopulmonary responses to maximal exercise testing in obese adolescents were searched: cardiopulmonary exercise tests with respiratory gas exchange measurements of peak oxygen uptake (VO2peak) were performed and comparisons between obese and lean adolescents were made. Study quality was assessed using a standardized item list. By meta-analyses VO2peak, peak cycling power output (Wpeak) and peak heart rate (HRpeak) were compared between groups. Nine articles were selected (333 obese vs. 145 lean adolescents). VO2peak (L min −1 ), HRpeak and Wpeak were not different between groups (P ≥ 0.10), while a trend was found for a reduced VO2peak (mL min −1 kg −1 lean tissue mass) (P = 0.07) in obese vs. lean adolescents. It remained uncertain whether anomalous cardiopulmonary responses occur during maximal exercise testing in obese adolescents. In conclusion, a trend was found for lowered VO2peak (mL min −1 kg −1 lean tissue mass) in obese vs. lean adolescents. Whether cardiopulmonary anomalies during maximal exercise testing would occur in obese adolescents remains uncertain. Studies are therefore warranted to examine the cardiopulmonary response during maximal exercise testing in obese adolescents.
  • References (28)
  • Citations (11)
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References28
Newest
#1Dominique Hansen (University of Hasselt)H-Index: 23
#2Romain Meeusen (Vrije Universiteit Brussel)H-Index: 52
Last. Paul Dendale (University of Hasselt)H-Index: 31
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In subjects with obesity, the implementation of long-term exercise intervention increases lean tissue mass and lowers adipose tissue mass. However, data indicate a blunted lipolytic response, and/or skeletal muscle protein synthesis, when subjects with obesity are exposed to acute endurance or resistance exercise, respectively. Therefore, subjects with obesity seem to display a suboptimal physiological response to acute exercise stimuli. It might be hypothesized that hormonal disturbances contri...
26 CitationsSource
#1Monique Mendelson (French Institute of Health and Medical Research)H-Index: 3
#2Anne-Sophie Michallet (French Institute of Health and Medical Research)H-Index: 1
Last. Patrice Flore (French Institute of Health and Medical Research)H-Index: 16
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Abstract The aim of this study was to examine ventilatory responses to training in obese adolescents. We assessed body composition, pulmonary function and ventilatory responses (among which expiratory flow limitation and operational lung volumes) during progressive cycling exercise in 16 obese adolescents (OB) before and after 12 weeks of exercise training and in 16 normal-weight volunteers. As expected, obese adolescents’ resting expiratory reserve volume was lower and inversely correlated with...
11 CitationsSource
#1Santiago Lorenzo (UTSW: University of Texas Southwestern Medical Center)H-Index: 10
#2Tony G. BabbH-Index: 18
Background The quantification and interpretation of cardiorespiratory fitness (CRF) in obesity is important for adequately assessing cardiovascular conditioning, underlying comorbidities, and properly evaluating disease risk. We retrospectively compared peak oxygen uptake ( o 2 peak) (ie, CRF) in absolute terms, and relative terms (% predicted) using three currently suggested prediction equations (Equations R, W, and G). Methods There were 19 nonobese and 66 obese participants. Subjects underwen...
31 CitationsSource
#2Arnt Erik TjønnaH-Index: 20
Last. Ulrik WisløffH-Index: 69
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Objectives To measure cardiac function before and after 3 months of aerobic interval training in obese adolescents and to compare the findings with those in lean counterparts. Design Exercise intervention study. Cardiac function was assessed by echocardiography and maximal oxygen uptake by ergospirometry. Setting The obese adolescents were referred from general practice to the St Olav University Hospital, Trondheim, Norway, and the control group was recruited from 2 schools. Participants Ten obe...
59 CitationsSource
#1Hassane Zouhal (University of Rennes)H-Index: 21
#2Georges Jabbour (University of Rennes)H-Index: 7
Last. Christophe Jacob (University of Balamand)H-Index: 16
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The aim of this study was to investigate plasma catecholamine [adrenaline (A) and noradrenaline (NA)] concentrations at rest and in response to maximal exercise in three different groups of adolescent girls. According to their body mass index, 34 adolescent girls aged 15–16 years were divided into three groups: a normal weight group (NO) (n = 11), an overweight group (OW) (n = 11) and an obese group (OB) (n = 12). Plasma A and NA concentrations were measured at rest during fasting conditions (A ...
7 CitationsSource
#1Jennifer L. BakerH-Index: 29
Last. Ram WeissH-Index: 34
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The prevalence of obesity among children and adolescents is on the rise. The majority of overweight or obese children are treated by primary health care providers including paediatricians, family practitioners, dieticians, nurses, and school health services - and not by specialists. The majority of obese children have no underlying medical disorder causing their obesity yet a significant proportion might suffer from obesity-related co-morbidities. This text is aimed at providing simple and pract...
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#1Gert Jan Van Der Heijden (BCM: Baylor College of Medicine)H-Index: 3
#2Zhiyue J. WangH-Index: 32
Last. Agneta L. Sunehag (BCM: Baylor College of Medicine)H-Index: 23
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The rise in obesity-related morbidity in children and adolescents requires urgent prevention and treatment strategies. Currently, only limited data are available on the effects of exercise programs on insulin resistance, and visceral, hepatic, and intramyocellular fat accumulation. We hypothesized that a 12-week controlled aerobic exercise program without weight loss reduces visceral, hepatic, and intramyocellular fat content and decreases insulin resistance in sedentary Hispanic adolescents. Tw...
152 CitationsSource
#1Kristen J. Nadeau (University of Colorado Denver)H-Index: 30
#2P. Zeitler (University of Colorado Denver)H-Index: 5
Last. Judith G. Regensteiner (University of Colorado Denver)H-Index: 58
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Context: The incidence of pediatric type 2 diabetes (T2D) is rising, with unclear effects on the cardiovascular system. Cardiopulmonary fitness, a marker of morbidity and mortality, is abnormal in adults with T2D, yet the mechanisms are incompletely understood. Objective: We hypothesized that cardiopulmonary fitness would be reduced in youth with T2D in association with insulin resistance (IR) and cardiovascular dysfunction. Design, Setting, and Participants: We conducted a cross-sectional study...
123 CitationsSource
#1Hala Youssef (University of Rennes)H-Index: 8
#2Carole Groussard (University of Rennes)H-Index: 14
Last. Arlette Gratas-Delamarche (University of Rennes)H-Index: 22
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Exercise-induced oxidative stress in overweight adolescent girls: roles of basal insulin resistance and inflammation and oxygen overconsumption
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Abstract Background and aims Heart rate (HR) response to exercise has not been fully described in the obese. We wanted to study the differences between obese and non-obese patients in HR behavior during an exercise stress test and to determine whether these differences influence exercise capacity. Methods and results We studied 554 patients (318 females) who underwent a treadmill exercise test. All subjects were in sinus rhythm. Patients with ischemic heart disease, with reduced ejection fractio...
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#1P. Bokov (French Institute of Health and Medical Research)
#2Christophe Delclaux (French Institute of Health and Medical Research)H-Index: 37
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#1Aliva De (CUMC: Columbia University Medical Center)H-Index: 1
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ABSTRACTIntroduction: Obesity affects about 40% of US adults and 18% of children. Its impact on the pulmonary system is best described for asthma.Areas covered: We reviewed the literature on PubMed...
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