IgG4 Overexpression Is Rare in Meningiomas with a Prominent Inflammatory Component: A Review of 16 Cases

Meningiomas with prominent inflammation are traditionally classified as “lymphoplasmacyte‐rich meningioma” ( LPM ). Both inflammatory and neoplastic meningeal proliferations have recently been linked to IgG 4 disease, although a potential association with LPM has not been previously explored. Sixteen meningiomas with inflammatory cells outnumbering tumor cells were further characterized by CD 3, CD 20, CD 68 and/or CD 163, CD 138, kappa, lambda,...