Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice

Gut microbiota is now known to control glucose metabolism. Previous studies have shown that probiotics and prebiotics may improve glucose metabolism, but their effects have not been studied in combination with drug therapy. The aim of this study was to investigate whether probiotics and prebiotics combined with drug therapy affect diabetic outcomes. Two different study designs were used to test gut microbiota modulating treatments with metformin...