ZAG, a lipid mobilizing adipokine, is downregulated in human obesity

The main goal of this study was to compare the expression of Zinc-α2-glycoprotein (ZAG), a recently described adipokine, in obese and lean subjects. ZAG expression was determined by Real-time PCR analysis in subcutaneous abdominal adipose tissue of eighteen young men, 9 lean (BMI=23.1±0.4 kg/m2) and 9 obese (34.7±1.2 kg/m2) with a similar habitual dietary intake of fat and physical activity, which were assessed by validated methods. Our data...