Photostability of antidotal oxime HI-6, impact on drug development

HI‐6 exhibits superior efficacy in the therapy of intoxication by different highly toxic organophosphorus nerve agents. Therefore HI‐6 is a promising candidate for the development of new antidotes against nerve agents. For ethical and safety reasons antidotes containing HI‐6 should get marketing authorization. Active pharmaceutical ingredients of medicinal products have to fulfil regulatory conditions in terms of purity and stability....