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CLINICAL CALORIMETRY XLV. PROLONGED MEAT DIETS WITH A STUDY OF KIDNEY FUNCTION AND KETOSIS

Published on Jul 1, 1930in Journal of Biological Chemistry4.106
Walter S. McClellan3
Estimated H-index: 3
,
Eugene F. Du Bois7
Estimated H-index: 7
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Abstract
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  • Citations (45)
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#1John D. Speth (UM: University of Michigan)H-Index: 22
Abstract This paper explores the role of vitamin C (ascorbic acid) in the foodways of hunter-gatherers—both ethnohistoric and Paleolithic—whose diet seasonally or over much of the year, of necessity, was comprised largely of animal foods. In order to stave off scurvy, such foragers had to obtain a minimum of about 10 mg per day of vitamin C. However, there is little to no vitamin C in muscle meat, being concentrated instead in various internal organs and brain. Even ruminant stomach contents, de...
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#1Guoyao Wu (A&M: Texas A&M University)H-Index: 101
A protein consists of amino acids (AA) linked by peptide bonds. Dietary protein is hydrolyzed by proteases and peptidases to generate AA, dipeptides, and tripeptides in the lumen of the gastrointestinal tract. These digestion products are utilized by bacteria in the small intestine or absorbed into enterocytes. AA that are not degraded by the small intestine enter the portal vein for protein synthesis in skeletal muscle and other tissues. AA are also used for cell-specific production of low-mole...
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#1Zsófia ClemensH-Index: 14
#2Csaba TóthH-Index: 4
The role of vitamin C at the physiological and cellular levels is indisputable. In line with this, blood level of vitamin C is inversely related to disease parameters such as risk of cancer, cardiovascular disease and mortality in prospective cohort and correlational studies. At the same time, adequately powered clinical intervention studies consistently provide no evidence for a beneficial effect of supplementing vitamin C. Here we provide a framework to resolve this apparent conflict. Besides ...
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#1Petr GrúzH-Index: 1
This chapter offers an unconventional review of lipid peroxidation in its relation to human nutrition and aging. Although emphasis is put on DNA damage as a key molecular target, other aspects of the oxidation of polyunsaturated fatty acids (PUFAs) in the body are covered. This includes the chemical stability of PUFAs, the meaning of their enzymatic oxidation for the immune system, spontaneous oxidation either endogenously in membranes or exogenously during food preparation, the modifications of...
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#1Ezdine BouhlelH-Index: 6
#2Roy ShephardH-Index: 2
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#1Nathalie L. Trottier (MSU: Michigan State University)H-Index: 19
#2Ryan Walker (MSU: Michigan State University)
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#1Jeff S. Volek (OSU: Ohio State University)H-Index: 70
#2Timothy Noakeschb (UCT: University of Cape Town)H-Index: 83
Last. Stephen D. Phinney (UC Davis: University of California, Davis)H-Index: 36
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AbstractA key element contributing to deteriorating exercise capacity during physically demanding sport appears to be reduced carbohydrate availability coupled with an inability to effectively utilize alternative lipid fuel sources. Paradoxically, cognitive and physical decline associated with glycogen depletion occurs in the presence of an over-abundance of fuel stored as body fat that the athlete is apparently unable to access effectively. Current fuelling tactics that emphasize high-carbohydr...
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#1William Barendse (CSIRO: Commonwealth Scientific and Industrial Research Organisation)H-Index: 34
Humans hunt or raise a wide variety of animals for meat, which vary from free-range to intensively reared. These animals form a valuable part of human nutrition. Their tissues, including the fat, contain vitamin and other essential nutrients necessary for health. However, animal fat from ruminants and other land mammals is usually regarded as saturated. The purpose of this review is partly to examine the basis for the saturated fat hypothesis of cardiovascular disease given more recent research,...
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#1Rainer J. KlementH-Index: 20
#2Thomas FrobelH-Index: 1
Last. Ulrike KämmererH-Index: 37
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Background: Ketogenic diets (KDs) have gained some popularity not only as effective weight-loss diets and treatment options for several diseases, but also among healthy and physically active individuals for various reasons. However, data on the effects of ketosis in the latter group of individuals are scarce. We therefore collected pilot data on the physiological response to a self-prescribed ketogenic diet lasting 5-7 weeks in a small cohort of healthy and physically active individuals. Methods...
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After 30 years of policy based on the Diet Heart (low-fat) Hypothesis, obesity and type 2 diabetes are now an epidemic. Recently published research seriously questions the dangers of dietary saturated fats and also any potential health benefits of a low-fat diet for the general population. In the context of these seismic changes in evidence-based nutrition, it is time to revisit our perspective of carbohydrate-restricted diets, not only for weight loss but also for the long-term management of co...
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