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"Double depression": superimposition of acute depressive episodes on chronic depressive disorders.

Published on Apr 1, 1982in American Journal of Psychiatry 13.65
· DOI :10.1176/ajp.139.4.438
Martin B. Keller116
Estimated H-index: 116
Robert W. Shapiro14
Estimated H-index: 14
Although ‘ ‘double depression ‘ ‘-major depressive disorder superimposed on an underlying chronic depression-is a f requent phenomenon, the concept has not been well formulated clinically and has rarely been described in the research literature. The authors found that 1) 26% of 101 patients who met the criteria for major depressive disorder had an underlying chronic depressive disorder of at least 2 years’ duration, 2) “recovery” ratesfor patients with superimposed depression differed greatly depending on whether recovery was defined as recovery from the major depressive disorder only or recovery from both disorders, and 3) patients with superimposed depression relapsed at a significantly higher rate immediately after recovery from the acute episode of depression than did patients without superimposed depression.
  • References (9)
  • Citations (284)
Published on Sep 1, 1981in Journal of Affective Disorders 4.08
Robert W. Shapiro14
Estimated H-index: 14
(Massachusetts Mental Health Center),
Martin B. Keller116
Estimated H-index: 116
(Harvard University)
Abstract Results from 121 patients with major depressive disorder followed-up at 6 months with a new comprehensive follow-up schedule, the Longitudinal Interval Follow-Up Evaluation (LIFE) indicate that: 1. (1) Forty percent of patients had not recovered from the index episode 6 months after inclusion; 2. (2) Of those patients who recovered, 19% relapsed into another RDC affective episode by the time of the 6-months follow-up, and an additional 24% developed some subsequent affective symptoms by...
50 Citations Source Cite
Published on Jul 1, 1980in Archives of General Psychiatry
Hagop S. Akiskal96
Estimated H-index: 96
Ted L. Rosenthal17
Estimated H-index: 17
+ 3 AuthorsAlice Scott-Strauss4
Estimated H-index: 4
• Early-onset characterological depressions are distinguished from late-onset chronic depressions that complicate the longterm course of unipolar and nonaffective illnesses. In turn, characterological depressions are divisible into at least two subtypes: (1) "Subaffective dysthymias" have even sex distribution, are often complicated by superimposed depressive episodes, rapid eye movement latency is shortened, and they tend to respond to tricyclics or lithium carbonate. In brief, they share many ...
279 Citations Source Cite
Published on Jun 1, 1980in Journal of Affective Disorders 4.08
Bruce J. Rounsaville90
Estimated H-index: 90
(Yale University),
Diane E. Sholomskas16
Estimated H-index: 16
(Yale University),
Brigitte A. Prusoff54
Estimated H-index: 54
(Yale University)
Abstract The current study was devised to assess the utility of Research Diagnostic Criteria (RDC) categories used to classify minor mood disorders. Similar categories are to be used in the APA's Diagnostic and Statistical Manual , 3rd edition. The patient sample consisted of 64 consecutive admissions to a double-blind trial of amitriptyline, perphenazine and the combination as treatment for depression. Patients who met RDC for a current episode of major depressive disorder were given 4 weeks of...
45 Citations Source Cite
Published on Jul 1, 1979in Archives of General Psychiatry
Martin M. Katz20
Estimated H-index: 20
(NIH: National Institutes of Health),
Steven Secunda5
Estimated H-index: 5
(NIH: National Institutes of Health)
+ 1 AuthorsStephen H. Koslow34
Estimated H-index: 34
(NIH: National Institutes of Health)
• This is a report on the history and implications of the collaborative effort that evolved from the 1969 National Institute of Mental Health conference on the psychobiology of depression. The major issues identified at that time were the need to (1) assess relative validities of current systems of nosology and (2) retest critical biological hypotheses concerning the etiology and nature of the depressive disorders. Research was required that would be multidisciplinary and involve clinical settin...
192 Citations Source Cite
Published on Jun 1, 1978in Archives of General Psychiatry
Robert L. Spitzer85
Estimated H-index: 85
Jean Endicott93
Estimated H-index: 93
Eli Robins48
Estimated H-index: 48
• A crucial problem in psychiatry, affecting clinical work as well as research, is the generally low reliability of current psychiatric diagnostic procedures. This article describes the development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC). The RDC are being widely used to study a variety of research issues, particularly those related to genetics, psychobiology of selec...
5,539 Citations Source Cite
Published on Jan 1, 1976in Archives of General Psychiatry
Joseph L. Fleiss66
Estimated H-index: 66
David L. Dunner58
Estimated H-index: 58
+ 1 AuthorsRonald R. Fieve43
Estimated H-index: 43
• The life table is presented as the method of choice for analyzing data from longitudinal studies in which the outcome under study occurs randomly and in which patients are followed up varying lengths of time. We discuss the superiority of the life table to methods typically used, the calculation of its entries, and some of the clinical uses that can be made of its results. The method is applied to follow-up data on manic-depressive patients maintained with prophylactic lithium carbonate or wit...
82 Citations Source Cite
Published on Apr 1, 1960in American Sociological Review 5.39
Vera Norris1
Estimated H-index: 1
title does not really reflect the contents of this volume for the stress is on forensic and drug toxicology. The editors apparently did not think they should get experts to write about such plebian methods as those in the visual spectrophotometric range or those employing wet test methods. With this book and the aid of a good library and an exceptionally well equipped laboratory, not to speak of a specially trained staff, the physicochemical types of analysis discussed could be performed. This v...
47 Citations Source Cite
Published on Mar 1, 1948in Journal of Nervous and Mental Disease 1.86
Paul E. Huston9
Estimated H-index: 9
Lillian M. Locher2
Estimated H-index: 2
IN THIS report are compared the courses of illness of two series of patients with involutional psychoses, one treated with electric shock and the other not so treated. An analysis of certain factors possibly related to the course is also presented. Involutional psychosis is a psychosis occurring in middle life and the following years, without evidence of either "organic" intellectual defects or a previous affective disorder. The subtype melancholia is characterized mainly by agitation and depres...
34 Citations Source Cite
Cited By284
Published on Jun 26, 2019in The Canadian Journal of Psychiatry
Daniel N. Klein72
Estimated H-index: 72
(SBU: Stony Brook University)
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Published on May 1, 2019in Journal of Humanistic Psychology 1.59
Golan Shahar36
Estimated H-index: 36
(Yale University)
Pavlo, Flanagam, Leither, and Davidson attempt to reconcile the recovery movement in mental health service with a formal diagnostic practice is as courageous as it is timely. Acknowledging this, I note several points of convergence and divergence with the authors’ views. Points of convergence include (1) the inevitability of a diagnostic system when working with (severe) mental illness, (2) the importance of going beyond signs and symptoms in capturing the unique characteristics of the person, (...
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Published on Feb 4, 2019in Epidemiology and Psychiatric Sciences 6.40
Mila Kingsbury11
Estimated H-index: 11
Ewa Sucha2
Estimated H-index: 2
+ 4 AuthorsIan Colman31
Estimated H-index: 31
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Published on Jan 1, 2018in Depression and Anxiety 4.93
Stephanie M. Case2
Estimated H-index: 2
(UIndy: University of Indianapolis),
Manisha Sawhney1
Estimated H-index: 1
(University of Mary),
Jesse C. Stewart17
Estimated H-index: 17
(IUPUI: Indiana University – Purdue University Indianapolis)
BACKGROUND Although depression is a risk factor for cardiovascular disease (CVD), it is unknown whether this risk varies across depressive disorder subtypes. Thus, we investigated atypical major depressive disorder (MDD) and double depression as predictors of new-onset CVD in a nationally representative sample of U.S. adults. METHODS Prospective data from 28,726 adults initially free of CVD who participated in Wave 1 (2001–2002) and Wave 2 (2004–2005) of the National Epidemiologic Survey on Alco...
5 Citations Source Cite
Published on Nov 1, 2017in Psychological Science in the Public Interest 22.25
Lee Anna Clark68
Estimated H-index: 68
(ND: University of Notre Dame),
Bruce Cuthbert1
Estimated H-index: 1
+ 2 AuthorsGeoffrey M. Reed23
Estimated H-index: 23
(WHO: World Health Organization)
The diagnosis of mental disorder initially appears relatively straightforward: Patients present with symptoms or visible signs of illness; health professionals make diagnoses based primarily on these symptoms and signs; and they prescribe medication, psychotherapy, or both, accordingly. However, despite a dramatic expansion of knowledge about mental disorders during the past half century, understanding of their components and processes remains rudimentary. We provide histories and descriptions o...
50 Citations Source Cite
Published on Aug 24, 2017
Despite the greater prevalence of chronic depression, there are controversial questions about the clinical and psycho-pathological structure of the course and determinants of chronic depressive disorder. There is an abundance of terms applicable to the long-term depressive disorders, and significant discrepancies in the assessment of these states. The allocation of chronic depression is not provided according to ICD-10 (1994). Chronic depression and dysthymia combine into one diagnosis "persiste...
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Published on Mar 1, 2017in Asia-pacific Psychiatry 1.14
Yuan Feng3
Estimated H-index: 3
(Capital Medical University),
Sha Sha3
Estimated H-index: 3
(Capital Medical University)
+ 17 AuthorsYi Ru Fang2
Estimated H-index: 2
(SJTU: Shanghai Jiao Tong University)
Introduction Little has been reported about the demographic and clinical features of major depressive disorder (MDD) with comorbid dysthymia in Chinese patients. This study examined the frequency of comorbid dysthymia in Chinese MDD patients together with the demographic and clinical correlates and prescribing patterns of psychotropic drugs. Methods Consecutively collected sample of 1178 patients with MDD were examined in 13 major psychiatric hospitals in China. Patients' demographic and clinica...
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Published on Nov 16, 2016in Nordic Journal of Psychiatry 2.06
Per Bech67
Estimated H-index: 67
(Copenhagen University Hospital),
Lars Vedel Kessing50
Estimated H-index: 50
Jens Bukh63
Estimated H-index: 63
AbstractBackground: In long-term follow-up studies on depression, the Eysenck Neuroticism Scale (ENS) at the score level of dysthymia has been found to be valid at predicting poor outcome.Aims: The ENS dysthymia level was compared with the Beck Depression Inventory (BDI) level to predict the prevalence of depressive symptoms at the 5-year follow-up of patients initially diagnosed with first episode depression using the Hamilton Depression Scale (HAM-D) to express depressive symptoms.Methods: A t...
4 Citations Source Cite
Published on Oct 9, 2016in Iranian Journal of Psychiatry
Sajedeh Hamidian1
Estimated H-index: 1
(Shiraz University of Medical Sciences),
Abdollah Omidi7
Estimated H-index: 7
(KAUMS: Kashan University of Medical Sciences)
+ 1 AuthorsGhasem Naziri3
Estimated H-index: 3
(IAU: Islamic Azad University)
The concept of depression has been recognized among the physicians. Avicenna, in his book ?Canon of Medicine, referred to depression as "melancholy" and defined it as a disorder in which ?the thought deviates from the natural path leading to destruction and fear. He believes that this ?disorder is caused by ill-tempered dry and cold humor. In his opinion, dry and cold humor is ?opposed to and hurts the spirit (1).?Dysthymia can be initially differentiated from major depression by its chronic nat...
Anne Christie Timm González1
Estimated H-index: 1
Zuleide M. Ignácio7
Estimated H-index: 7
(Unesc: Universidade do Extremo Sul Catarinense)
+ 5 AuthorsJoao L De Quevedo59
Estimated H-index: 59
(Unesc: Universidade do Extremo Sul Catarinense)
Objective The present study assessed the prevalence of depressive disorders and associated factors in a sample of elderly persons in the south of Santa Catarina. Methods A cross-sectional study based on population data was performed, evaluating 1021 elderly individuals aged between 60 and 79 years. Home interviews were carried out using the Portuguese version of the Mini International Neuropsychiatric Interview (MINI), in order to collect demographic data, information on hypertension and reports...
1 Citations Source Cite