Upside-Down Protein Crystallization: Designing Microbatch Experiments for Microgravity

: The benefits of protein crystal growth in microgravity are well documented. The crystallization vessels currently employed for microgravity crystallization are far from optimal with regards to cost, sample volume, size, and ease of use. The use of microbatch experiments is a favorable alternative in each respect: 96 experiments of 0.5–2 μL volumes can be performed in a single microtiter tray measuring 5 × 8 cm and costing ££1 sterling each. To...