Journal of Functional Foods
Papers 3697
1 page of 370 pages (3,697 results)
Abstract Konjac glucomannan is safely and widely used in the functional food industry. Compared with glucomannan, glucomannan oligosaccharides have higher water solubility making them easier to absorb and utilize. These oligosaccharides are also associated with many biological activities. A novel glucomannan hydrolase PpGluA with high activity and substrate specificity which releases a series of konjac glucomannan oligosaccharides having DP 2–9 is described here. Selenium is one of the essential...
Abstract Aging is a global challenge. Many studies reported that the accumulation of ROS and oxidative stress could be the most important causative factors for aging. Phenolic, flavonoids, and melanoidins possess potent of ROS scavenging ability. In this study, brown black wolfberry (BBW) was prepared via the Maillard Reaction (MR) and its anti-aging potential was explored using the Drosophila melanogaster and d -gal induced aging mice as the animal model. Results showed that total phenolic and ...
Abstract Soybean peptides Maillard reaction products (SMRPs) as a flavor enhancer were prepared to investigate its potential prebiotic activities on modulating gut microbiota to alleviate aging-related disorders in d -galactose-induced ICR mice. The mice were divided into six groups during 6 weeks experimental period, including normal control, natural aging control, d -galactose aging group, low, medium and high dose SMRPs groups (200, 400 and 800 mg/kg/day). Results showed that d -galactose agi...
Abstract EGCG is an important bioactive component of green tea, which has the biological functions of antioxidant and antitumor. However, the stability of EGCG is poor, the absorption rate is low, and the bioavailability needs to be improved. In this study, the factors influencing the bioavailability of oral EGCG and the commonly used methods to improve its bioavailability were reviewed. The results showed that oral EGCG was not stable in intestinal and blood environment, most of EGCG was not ab...
Abstract Oxidative stress and inflammation are two important pathological mechanisms in diabetic nephropathy (DN). Aucubin (AU), a natural iridoid glucoside, possessing remarkable anti-inflammatory and anti-oxidation activity, has been used to treat diabetic complications. However, underlying mechanism of protective action in DN remains unclear. In the present study, AU significantly alleviated albuminuria, glomerular extracellular matrix expansion, renal fibrosis, and inflammation caused by dia...
Abstract Chemoprevention leverages the ability of natural products to interfere with disease onset and progression. In this study, the preventive effect of dietary inclusion with Crassocephalum rubens at 0, 2.5, 5 and 10% levels on colorectal carcinogenesis initiated by N-methyl-N-nitrosourea (MNU) instillations in male Wistar rats was explored following 12 weeks of treatment. Results showed that dietary inclusion with C. rubens particularly at the 10% level significantly lowered lipid peroxidat...
Abstract Pressed degreased walnut meal (WM) was prepared from walnut kernel by cold-press deoil. It was rich in polyphenols with high activities of lowering lipids, antioxidation, anti-inflammation, and others, but the hypoglycemic activity has scarcely been reported. The purpose of this research was to investigate the preventive effect of the extracts of WM (WMP) on T2DM rats and the regulation of WMP on intestinal flora. Some results showed that WMP significantly held FBG, FINS and GSP, OGTT, ...
Abstract Peptides from sesame cake (PSC) have been reported to exert a beneficial effect on aging. Parkinson’s disease (PD) is an age-related disorder, which manifests as Lewy body formation and dopaminergic dysfunction. To investigate the effects of PSC on PD-associated pathologies and to identify possible underlying molecular mechanisms, this study employed two transgenic Caenorhabditis elegans models: NL5901, which expressed α-synuclein (α-syn) in muscle cells, and BZ555, which expressed GFP ...
Abstract Fucoxanthin (Fx) is a major xanthophyll in Undaria pinnatifida (wakame) and is one of the potent carotenoids against cancer development. However, the cancer preventive function of high fucoxanthin (Fx-high) wakame itself has not been well investigated. Therefore, we cultivated Fx-high wakame and investigated the effect of this alga on a AOM/DSS carcinogenesis mouse model. Fx-high wakame (Fx 30 mg/kg body weight) significantly decreased the number of cells that compose the tumor microenv...
#1Li-Tao TongH-Index: 10
#2Zhiyuan JuH-Index: 1
Last.Sumei ZhouH-Index: 2
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Abstract Rice α-globulin has been reported to possess anti-atherosclerotic activity, but the key peptides in the rice α-globulin and the underlying mechanisms remain unknown. The anti-atherosclerotic effects of the rice α-globulin peptides YYGGEGSSSEQG and SESEM were observed in apolipoprotein E-deficient (ApoE−/−) mice in this study. The synthetic peptides were orally administered to ApoE−/− mice at a dose of 100 mg/kg body weight. The lesion area in the aorta and the aortic root were significa...
Top fields of study
Food science
Diabetes mellitus