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#1Takako TabataH-Index: 13
#2Matthew PetittH-Index: 11
Last.Lenore PereiraH-Index: 38
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Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown. We measured the efficacy of human monoclonal antibodies (mAbs) to HCMV attachment/entry factors glycoprotein B (gB) and the pentameric complex, gH/gL-pUL128–131, in preventing infection and spread of a clinical strain in primary placental cells and explants of developing anchoring villi. A total of 109 e...
#1Jianxing YuH-Index: 6
#2Xiang RenH-Index: 6
Last.Zhongjie LiH-Index: 19
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Influenza vaccination is recommended for nurses in China but is not mandatory or offered free of charge. The main objective of this study was to determine influenza vaccination coverage and the principal factors influencing influenza vaccination among nurses in China. During 22 March–1 April 2018, we conducted an opt-in internet panel survey among registered nurses in China. Respondents were recruited from an internet-based training platform for nurses. Among 22,888 nurses invited to participate...
Influenza virus imprinting is now understood to significantly influence the immune responses and clinical outcome of influenza virus infections that occur later in life. Due to the yearly cycling of influenza viruses, humans are imprinted with the circulating virus of their birth year and subsequently build a complex influenza virus immune history. Despite this knowledge, little is known about how the imprinting strain influences vaccine responses. To investigate the immune responses of the impr...
#2Mieghan BruceH-Index: 6
Last.I.D. RobertsonH-Index: 39
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Adequate vaccination coverage of free roaming dogs (FRD) against canine rabies is not achieved primarily due to difficulties in administering parenteral vaccinations to this population. One factor associated with this difficulty is the tendency of FRD to form groups, which increases their aggressive behavior, resulting in a significant risk of dog-bites for the vaccinators. This study investigated factors that influenced FRD forming groups and their home-ranges, using data obtained from photogra...
#1Arnaud Tarantola (Pasteur Institute)H-Index: 20
#2Sowath Ly (Pasteur Institute)H-Index: 18
Last.Simon Cauchemez (Pasteur Institute)H-Index: 37
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Abstract Rabies causes 60,000 deaths worldwide annually. Rabies post-exposure prophylaxis is highly effective but often geographically and financially beyond reach in endemic developing countries. We conducted a retrospective study on clinical outcome at ≥6 months in 3318 Cambodians who received intradermal Vero cell vaccine post-exposure prophylaxis after a bite by a rabid or sick-looking but untested dog in 2003–2014. An external expert panel examined verbal autopsy reports to identify rabies ...
#1Thomas CherianH-Index: 28
#2Kathleen MoralesH-Index: 2
Last.Philipp Lambach (WHO: World Health Organization)H-Index: 9
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Abstract Health workers represent an important target group for seasonal influenza vaccination because of their increased risk of infection as well as the risk of transmitting infection to vulnerable patients in the health care setting. Moreover, seasonal vaccination of health workers contributes to pandemic preparedness. However, many countries, especially in Africa and Asia, do not have policies for health worker influenza vaccination. In countries where such policies exist, vaccination covera...
#1J.R. Torres (Central University of Venezuela)
#2Luiza Helena Falleiros-Arlant (Metropolitan University)H-Index: 2
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Abstract Dengue disease represents a large and growing global threat to public health, causing a significant burden to health systems of endemic countries. For countries considering vaccination as part of their Integrated Management Strategy for Prevention and Control of Dengue, the World Health Organization currently recommends the first licensed dengue vaccine, CYD-TDV for: individuals aged 9 years or above from populations with high transmission rates, based on either seroprevalence criteria ...
#1Sonam WangchukH-Index: 9
#2Francisco Nogareda (WHO: World Health Organization)H-Index: 2
Last.Tshewang Dorji TamangH-Index: 1
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Abstract Background In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan’s elimination status. Methods A nationwide, three-stage, cluster seroprevalence survey was conducted among individuals aged 1–4, 5–17, and >20 years in 2017. Demographic information and children’s ...
#1Xiangxiang Chen (Fudan University)H-Index: 1
#2Abram L. Wagner (UM: University of Michigan)H-Index: 6
Last.Yihan Lu (Fudan University)H-Index: 1
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Abstract Background A hepatitis E (HepE) vaccine was developed and released in China in 2011. Uptake is currently very limited. The aims of this study were to characterize what public health professionals thought about promoting the HepE vaccine in Shanghai, China, and to develop realistic goals for the HepE vaccine based on this information. Methods Public health professionals from Shanghai and other jurisdictions of China were contacted to participate in in-depth qualitative interviews between...
#1Kristyna Rysava (Glas.: University of Glasgow)H-Index: 3
#2Mary Elizabeth Miranda (Global Alliance for Rabies Control)H-Index: 18
Last.Katie Hampson (Glas.: University of Glasgow)H-Index: 31
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Abstract Background Costs of rabies post-exposure prophylaxis (PEP) often remain high in regions where rabies has been controlled in dogs, presenting a challenge for sustaining rabies elimination programmes. We investigated the potential for bite patient risk assessments to improve PEP provision and surveillance in settings approaching elimination of dog-mediated rabies. Methods We conducted a longitudinal study of patients presenting to animal bite treatment centres (ABTCs) on the island provin...
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