Journal of Alzheimer's Disease
Papers 7374
1 page of 738 pages (7,374 results)
#1Pravat K. Mandal (National Brain Research Centre)H-Index: 22
#2Deepika Shukla (National Brain Research Centre)H-Index: 3
#1Insa FeinkohlH-Index: 10
#2Carola G Schipke (Humboldt University of Berlin)
Last. Oliver Peters (Humboldt University of Berlin)H-Index: 31
view all 7 authors...
BACKGROUND: Collection of cerebrospinal fluid (CSF) for measurement of amyloid-beta (Abeta) species is a gold standard in Alzheimer's disease (AD) diagnosis, but has risks. Thus, establishing a low-risk blood Abeta test with high AD sensitivity and specificity is of outmost interest. OBJECTIVE: We evaluated the ability of a commercially available plasma Abeta assay to distinguish AD patients from biomarker-healthy controls. METHOD: In a case-control design, we examined plasma samples from 44 AD ...
#1Gargi BanerjeeH-Index: 7
#2Gareth Ambler (UCL: University College London)H-Index: 27
Last. Ashley M. Groves (UCLH: University College Hospital)H-Index: 34
view all 15 authors...
BACKGROUND: There is limited data on cerebrospinal fluid (CSF) biomarkers in sporadic amyloid-beta (Abeta) cerebral amyloid angiopathy (CAA). OBJECTIVE: To determine the profile of biomarkers relevant to neurodegenerative disease in the CSF of patients with CAA. METHODS: We performed a detailed comparison of CSF markers, comparing patients with CAA, Alzheimer's disease (AD), and control (CS) participants, recruited from the Biomarkers and Outcomes in CAA (BOCAA) study, and a Specialist Cognitive...
#1Hyun Ju Yang (Jeju National University)
#2Na Ri Kang (Jeju National University)H-Index: 3
Last. Joon Hyuk Park (Jeju National University)H-Index: 15
view all 9 authors...
BACKGROUND: Apolipoprotein E (APOE) varepsilon4 allele carriers have an increased risk of late-onset Alzheimer's disease (AD). However, in the "Choosing Wisely" campaign for avoiding unnecessary medical tests, treatments, and procedures, APOE genetic testing is not recommended as a predictive test for AD. OBJECTIVE: The aim of this study was to investigate the potential value of APOE genetic testing in a specific clinical context. METHODS: Subjects with poor performance in the Korean version of ...
#1Ya-Juan Wang (Dalian Medical University)
#2Hao Hu (Qingdao University)H-Index: 1
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BACKGROUND: Recent studies have shown that amyloid-beta (Abeta) burden influenced white matter (WM) integrity before the onset of dementia. OBJECTIVE: To assess whether the effects of Abeta burden on WM integrity in cognitively normal (CN) individuals were regionally specific. METHODS: Our cohort consisted of 71 CNs from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database who underwent both AV45 amyloid-PET and diffusion tensor imaging. Standardized uptake value ratio (SUVR) was comp...
#1Hermine Counil (French Institute of Health and Medical Research)
#2Slavica Krantic (French Institute of Health and Medical Research)H-Index: 22
Nanosized extracellular vesicles, known as exosomes, are produced by all cell types in mammalian organisms and have been recently involved in neurodegeneration. In the brain, both glia and neurons give rise to exosomes, which contribute to their intercellular communication. In addition, brain-derived exosomes have a remarkable property to cross the blood-brain-barrier bi-directionally. In this line, exosomes of central origin have been identified in peripheral circulation and already considered ...
#1Marek Alifier (UMB: Medical University of Białystok)H-Index: 2
#2Bob Olsson (University of Gothenburg)H-Index: 30
Last. Johannes Kornhuber (FAU: University of Erlangen-Nuremberg)H-Index: 77
view all 13 authors...
BACKGROUND: Anesthesia and surgery is commonly associated with central nervous system sequelae and cognitive symptoms, which may be caused by neuronal injury. Neuronal injury can be monitored by plasma concentrations of the neuronal biomarkers tau and neurofilament light protein (NFL). Currently, there are no studies examining whether neuronal injury varies between surgical procedures. OBJECTIVE: Our aim was to investigate if neuronal damage is more frequent after cardiac than after otolaryngeal...
#1Michelle Lai (University of Melbourne)H-Index: 18
#2Matthew J. Sharman (RMIT: RMIT University)H-Index: 31
Last. Colin L. Masters (University of Melbourne)H-Index: 129
view all 11 authors...
#1Kaitlin B. Casaletto (UCSF: University of California, San Francisco)H-Index: 11
#2Miguel Arce Rentería (Columbia University)H-Index: 1
Last. Joel H. Kramer (UCSF: University of California, San Francisco)H-Index: 89
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#1Shi-Dong Chen (Fudan University)
#2Hong-Qi Li (Fudan University)
Last. Jin-Tai YuH-Index: 48
view all 9 authors...
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