Journal of Orthopaedic Research
Papers 6722
1 page of 673 pages (6,722 results)
#1David GrevensteinH-Index: 1
#2Juliane HeiligH-Index: 5
Last. Anja Niehoff (German Sport University Cologne)H-Index: 16
view all 7 authors...
Knee osteoarthritis (OA) involves several structures and molecules in the joint, which interact in a pathophysiological process. One of these molecules is the cartilage oligomeric matrix protein (COMP). Elevated COMP levels in the synovial fluid as well as in the serum have been described in OA patients. However, this has not been described in the infrapatellar fat pad (IPFP) tissue before. In this prospective trial, we collected 14 IPFPs from patients with high-grade OA (mean age 63.8 +/- 17.6 ...
#1Jeffrey R. Talarek (HSS: Hospital for Special Surgery)H-Index: 2
#2Alex N Piacentini (HSS: Hospital for Special Surgery)
Last. Christopher L. Mendias (Cornell University)H-Index: 25
view all 9 authors...
Chronic rotator cuff tears are a common source of shoulder pain and disability. Patients with rotator cuff tears often have substantial weakness, fibrosis, and fat accumulation, which limit successful surgical repair and postoperative rehabilitation. The Murphy Roths Large (MRL) strain of mice have demonstrated superior healing and protection against pathological changes in several disease and injury conditions. We tested the hypothesis that, compared with the commonly used C57Bl/6 (B6) strain, ...
#1Jonathan-James Eno (HSS: Hospital for Special Surgery)
#2Andreas Kontaxis (HSS: Hospital for Special Surgery)H-Index: 10
Last. Samuel A. Taylor (HSS: Hospital for Special Surgery)H-Index: 19
view all 11 authors...
Functional outcomes of subscapularis (SSc) repair following reverse shoulder arthroplasty (RSA) remains controversial. SSc repair in combination with glenosphere lateralization was reported to yield worse clinical outcomes compared with the non-lateralized glenosphere. The aim of this biomechanical study was to investigate how glenosphere lateralization and different re-insertion sites can affect the biomechanics of the SSc after RSA. Nine patient-specific RSA shoulder models were created from p...
#1Bruce D. Beynnon (UVM: University of Vermont)H-Index: 62
#2Niccolo M. Fiorentino (UVM: University of Vermont)H-Index: 9
Last. Carl W. Imhauser (HSS: Hospital for Special Surgery)H-Index: 17
view all 8 authors...
Combined injury to the anterior cruciate ligament (ACL) and meniscus is associated with earlier onset and increased rates of post-traumatic osteoarthritis compared with isolated ACL injury. However, little is known about the initial changes in joint structure associated with these different types of trauma. We hypothesized that trauma to the ACL and lateral meniscus has an immediate effect on morphometry of the articular cartilage and meniscus about the entire tibial plateau that is more pronoun...
#1Harvey A. Oliver (MU: University of Missouri)H-Index: 1
#2Chantelle C. Bozynski (MU: University of Missouri)H-Index: 9
Last. James L. Cook (MU: University of Missouri)H-Index: 34
view all 7 authors...
This study characterizes outcomes associated with subchondroplasty (SCP) versus SCP enhanced with platelet-rich plasma (PRP) or bone marrow aspirate concentrate (BMC) treatment of impact-induced subchondral bone marrow lesions (BML) using a validated preclinical canine model. With IACUC approval, purpose-bred research hounds (n = 24) underwent arthroscopic impact injury (40 N) to both medial femoral condyles. At 3 months, functional assessments, arthroscopy, and magnetic resonance imaging (MRI) ...
#1Adam Samuel Galbraith (National University of Ireland, Galway)H-Index: 1
#2Clara Sanz-Nogués (National University of Ireland, Galway)H-Index: 4
Last. Colin G. Murphy (National University of Ireland, Galway)H-Index: 3
view all 5 authors...
Cynthia Coleman acknowledges granted funding support from the Diabetes Ireland Research Alliance/Medical Research Charity Group/Health Research Board Joint Funding Scheme (HRB-MRCG-2016-2). The authors have no professional or financial affiliations that relate to or influence the contents of this publication.
#1Penny R. Atkins (UofU: University of Utah)H-Index: 5
#2Niccolo M. Fiorentino (UVM: University of Vermont)H-Index: 9
Last. Andrew E. AndersonH-Index: 26
view all 7 authors...
Femoroacetabular impingement syndrome (FAIS) may alter the kinematic function of the hip, resulting in pain and tissue damage. Previous motion analysis studies of FAIS have employed skin markers, which are prone to soft tissue artifact and inaccurate calculation of the hip joint center. This may explain why the evidence linking FAIS with deleterious kinematics is contradictory. The purpose of this study was to employ dual fluoroscopy (DF) to quantify in vivo kinematics of patients with cam FAIS ...
#1Jonathan D. Freedman (BU: Boston University)H-Index: 11
#2Daniel J. Ellis (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
Last. Mark W. Grinstaff (BU: Boston University)H-Index: 62
view all 8 authors...
Magnetic resonance imaging (MRI) and computed tomography (CT) are widely used to image cartilage and their diagnostic capability is enhanced in the presence of contrast agents. The aim of the study is to directly compare the performance between commercial anionic MRI (Gd(DTPA), Gd2-) and CT (Ioxaglate, Iox1-) contrast agents with novel cationic MRI (Gd(DTPA)Lys2 , Gd4+) and CT (CA4+) contrast agents for assessment of cartilage mechanical and biochemical properties using the ex vivo human osteoar...
#1Pichaya Thanindratarn (UCLA: University of California, Los Angeles)H-Index: 1
#2Xiaoyang Li (UCLA: University of California, Los Angeles)H-Index: 3
Last. Zhenfeng Duan (UCLA: University of California, Los Angeles)H-Index: 42
view all 6 authors...
Osteosarcoma (OSA) is the most common primary bone malignancy overall and is responsible for considerable adolescent mortality. Approximately 850 patients are newly diagnosed with OSA in the United States each year. While the 5-year survival rate for localized OSA has improved from <20% over 40 years ago to over 65% today, progress has dwindled over the past three decades. Therapeutic stagnation has occurred, in part, as a result of limited preclinical models and the overall heterogeneity of OSA...
#1Satoru Egawa (Tokyo Medical and Dental University)H-Index: 2
#2Keigo Hirai (Tokyo Medical and Dental University)H-Index: 1
Last. Shinichi Sotome (Tokyo Medical and Dental University)H-Index: 18
view all 8 authors...
Osteomyelitis remains one of the most challenging disorders for orthopedic doctors despite the advancement of therapeutic techniques. The purpose of this study was to investigate the feasibility of local antibiotic administration using hydroxyapatite/collagen (HAp/Col) as a drug delivery system. We hypothesized that higher adsorbability of antibiotics onto HAp/Col will result in more efficacious activity and therefore, treatment of osteomyelitis. Eight antibiotics were examined in this study: am...
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