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Neuropsychiatric Disease and Treatment
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#1Haiyang WangH-Index: 12
#2Lanxiang LiuH-Index: 8
Last. Wei ZhouH-Index: 1
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Background: Negative symptoms in schizophrenia are associated with impairments in social and cognitive functioning leading to substantial long-term disability. Available antipsychotic treatments have demonstrated only modest benefit in the improvement of negative symptoms. Objective: To compare improvements in negative symptoms among patients treated with paliperidone palmitate 3-month (PP3M) or paliperidone palmitate 1-month (PP1M) long-acting injectable (LAI) formulations. Methods: Data from a...
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Aim: Post-stroke depression (PSD) is one of the most frequent neuropsychiatric disorders associated with stroke characterized by depression. The neuroplasticity hypothesis postulates that loss of brain-derived neurotrophic factor (BDNF) plays a major role in pathophysiology of PSD, and restoration of it may represent a critical mechanism underlying antidepressant efficacy. Methods: In previous studies, we designed a new fusion gene, HA2TAT-BDNF, and cloned it into adenovirus associated virus (AA...
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Objective: To study predictors of the number of electroconvulsive therapy (ECT) sessions required for symptom remission in psychiatric patients. Patients and Methods: We conducted chart reviews for 95 patients whose condition remitted following inpatient ECT. We analyzed the clinical characteristics of the patients and compared the number of ECT sessions between adult (age 18-59 years) and elderly (age >/= 60 years) patients. Results: The overall mean +/- SD of the number of ECT sessions was 11....
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Psychiatry
Physical therapy
Disease
Medicine
Schizophrenia