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M.R. Graham , Yaodong Gu6
Estimated H-index: 6
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Peter Evans8
Estimated H-index: 8
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This article was published open access in International Journal of Advanced Engineering Research and Science on 01 July 2017, available at http://dx.doi.org/10.22161/ijaers.4.7.26
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Joaquim Bellmunt62
Estimated H-index: 62
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Ronald de Wit43
Estimated H-index: 43
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David J. Vaughn39
Estimated H-index: 39
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BackgroundPatients with advanced urothelial carcinoma that progresses after platinum-based chemotherapy have a poor prognosis and limited treatment options. MethodsIn this open-label, international, phase 3 trial, we randomly assigned 542 patients with advanced urothelial cancer that recurred or progressed after platinum-based chemotherapy to receive pembrolizumab (a highly selective, humanized monoclonal IgG4κ isotype antibody against programmed death 1 [PD-1]) at a dose of...
Ref 21Cited 369
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Julie R. Brahmer57
Estimated H-index: 57
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Karen L. Reckamp38
Estimated H-index: 38
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P. Baas8
Estimated H-index: 8
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BackgroundPatients with advanced squamous-cell non–small-cell lung cancer (NSCLC) who have disease progression during or after first-line chemotherapy have limited treatment options. This randomized, open-label, international, phase 3 study evaluated the efficacy and safety of nivolumab, a fully human IgG4 programmed death 1 (PD-1) immune-checkpoint–inhibitor antibody, as compared with docetaxel in this patient population. MethodsWe randomly assigned 272 patients to receive nivolum...
Ref 18Cited 2249
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2015 in Circulation [IF: 19.31]
Mary Fran Hazinski50
Estimated H-index: 50
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Jerry P. Nolan62
Estimated H-index: 62
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Richard Aickin12
Estimated H-index: 12
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The International Liaison Committee on Resuscitation (ILCOR) Advanced Life Support (ALS) Task Force performed detailed systematic reviews based on the recommendations of the Institute of Medicine of the National Academies1 and using the methodological approach proposed by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) Working Group.2 Questions to be addressed (using the PICO [population, intervention, comparator, outcome] format)3 were prioritized b...
Ref 459Cited 211
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The number of Brazilian scientific publications in the field of Cardiology and Cardiovascular Sciences in international indexing journals, different from other areas of Medicine, has remained largely stable over the past eight years. This situation does not reflect the significant increase in the number of senior researchers and the number of studies carried out in the several fields of activity that constitute our medical specialty. We currently observe the developme...
Cited 19
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D. J. Harriss7
Estimated H-index: 7
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Greg Atkinson29
Estimated H-index: 29
For publication in the International Journal of Sports Medicine (IJSM), studies involving human participants or animals must have been conducted in accordance with recognised ethical standards and national/international laws. At the very first submission stage, authors are required to confirm that these standards and laws have been adhered to by reading, and formally citing, this editorial within the methods section of their own manuscript. Authors who do not provide any inf...
Ref 9Cited 389
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Raymond C. Rosen93
Estimated H-index: 93
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Joseph C. Cappelleri52
Estimated H-index: 52
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N Gendrano1
Estimated H-index: 1
The International Index of Erectile Function (IIEF) is a widely used, multi-dimensional self-report instrument for the evaluation of male sexual function. It is has been recommended as a primary endpoint for clinical trials of erectile dysfunction (ED) and for diagnostic evaluation of ED severity. The IIEF was developed in conjunction with the clinical trial program for sildenafil, and has since been adopted as the 'gold standard' measure for efficacy assessment in clinical trials of ED. ...
Ref 60Cited 614
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Aleksandar Sekulic19
Estimated H-index: 19
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Michael R. Migden11
Estimated H-index: 11
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Anthony E. Oro35
Estimated H-index: 35
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Background Alterations in hedgehog signaling are implicated in the pathogenesis of basal-cell carcinoma. Although most basal-cell carcinomas are treated surgically, no effective therapy exists for locally advanced or metastatic basal-cell carcinoma. A phase 1 study of vismodegib (GDC-0449), a first-in-class, small-molecule inhibitor of the hedgehog pathway, showed a 58% response rate among patients with advanced basal-cell carcinoma. Methods In this multicenter, international
Ref 14Cited 609
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Holly J. Falk-Krzesinski8
Estimated H-index: 8
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Katy Börner31
Estimated H-index: 31
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Noshir Contractor35
Estimated H-index: 35
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The public health, social, technological, and environmental problems that impact our world are complex, but increasingly we are able to address them through scientific pursuit (1). The sophistication of these challenges necessitates cross-disciplinary engagement and collaboration, and the longer-term interaction of groups of investigators—team science (2-9). Such team-based research collaborations are also an essential feature of a robust translational research enterprise (1...
Ref 23Cited 92
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Publisher: Marsland Press1
Estimated H-index: 1
The Journal of American Science is an international journal with a purpose to enhance our natural and scientific knowledge dissemination in the world. Any valuable paper that describes natural phenomena and existence or any reports that convey scientific research and pursuit is welcome. Papers submitted could be reviews, objective descriptions, research reports, opinions/debates, news, letters, and other types of writings that are nature and science
Ref 187Cited 42 Source