Angiopreventive versus angiopromoting effects of allopurinol in the murine sponge model
Abstract
Recent data has indicated that, besides its classical therapeutic indication in hyperurecemia and gout, xanthine oxidase inhibitors can be used to various forms of ischemia and other types of tissue and vascular injuries. We tested the hypothesis that allopurinol, an inhibitor of xanthine oxidase (XO), might modulate acute and/or chronic inflammatory angiogenesis induced by subcutaneous implantation of synthetic matrix in mice. C57/BL6 male mice...
Paper Details
Title
Angiopreventive versus angiopromoting effects of allopurinol in the murine sponge model
Published Date
Sep 1, 2015
Journal
Volume
101
Pages
118 - 126
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